human serotonin 5 ht2a receptor Search Results


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Binding affinity or percentage inhibition of ST-2300 or PIM at different GPCRs.
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Binding affinity or percentage inhibition of ST-2300 or PIM at different GPCRs.
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Binding affinity or percentage inhibition of ST-2300 or PIM at different GPCRs.
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Binding affinity or percentage inhibition of ST-2300 or PIM at different GPCRs.
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Binding affinity or percentage inhibition of ST-2300 or PIM at different GPCRs.
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Binding affinity or percentage inhibition of ST-2300 or PIM at different GPCRs.
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Binding affinity or percentage inhibition of ST-2300 or PIM at different GPCRs.
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Binding affinity or percentage inhibition of ST-2300 or PIM at different GPCRs.
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Binding affinity or percentage inhibition of ST-2300 or PIM at different GPCRs.
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Image Search Results


Binding affinity or percentage inhibition of ST-2300 or PIM at different GPCRs.

Journal: Biomolecules

Article Title: The Novel Pimavanserin Derivative ST-2300 with Histamine H 3 Receptor Affinity Shows Reduced 5-HT 2A Binding, but Maintains Antidepressant- and Anxiolytic-like Properties in Mice

doi: 10.3390/biom12050683

Figure Lengend Snippet: Binding affinity or percentage inhibition of ST-2300 or PIM at different GPCRs.

Article Snippet: HEK293 cells with a stable expression of human 5-HT 1A , 5-HT 6 , 5-HT 7b , and D 2L (prepared with the use of Lipofectamine 2000), or CHO-K1 cells with plasmids containing the sequence coding for the human serotonin 5-HT 2A receptor (PerkinElmer), were maintained at 37 °C in a humidified atmosphere with 5% CO 2 and grown in Dulbecco’s Modified Eagle Medium containing 10% dialyzed fetal bovine serum and 500 μg/mL G418 sulfate.

Techniques: Binding Assay, Inhibition